Ubonelelo ngeFactory Sm04554 CAS 1360540-81-3 yokuNqatshwa kweNwele
Ingcaciso yeMveliso
Igama lemvelisoSM04554 (Dalosirvat)
Inombolo yeCAS: 1360540-81-3
Imbonakalo: Umgubo oMhlophe
Ubunyulu: 99%
Ingcaciso yeMveliso:
I-SM04554 (i-Dalosirvat) yi-activator ye-Wnt enamandla kunye nexabiso le-IC50 le-28-29 nM. Kuye kwafundwa ngendima yayo ekumodareyitheni iindlela zeselula ezibandakanyekayo ekuvuseleleni i-follicle yeenwele kunye nezinye iinkqubo zokuvuselela. Njengoko kuchaziwe kwi-patent WO2012024404A1, ikhompawundi 1, SM04554 inesithembiso esibalulekileyo kwizicelo zonyango, ngakumbi kunyango lokulahleka kweenwele.
Usetyenziso:
- Unyango lokulahleka kweenwele:
- I-SM04554 ibonise amandla njenge-ejenti ye-topical yokujongana ne-alopecia ye-androgenic kunye nezinye iimeko zokulahleka kweenwele ngokuvula indlela yokubonisa i-Wnt, ebalulekileyo kuphuhliso lwe-follicle yeenwele kunye nokuvuselelwa.
- Iyeza lokuhlaziya:
- Iphandwe ngokukwazi kwayo ukukhuthaza ukulungiswa kwezicubu kunye nokuhlaziywa ngokutsha kwendlela ye-Wnt yokumodareyitha.
- Uphando lwebhayoloji:
- Isebenza njengesixhobo sophando sokufunda indlela ye-Wnt yokubonisa kunye nendima yayo ekwandeni kwamaselula, ukwahlula, kunye neendlela zokulungisa.
Indlela yokwenza:
- I-Wnt Pathway Activation:
- I-SM04554 isebenze ngokufanelekileyo indlela yokubonisa i-Wnt, umlawuli ophambili wokukhula kweselula kunye nokulungiswa, ngakumbi kwizicubu ezifana neenwele kunye nolusu.
Iimbonakalo:
- Amandla aphezulu: I-IC50 ye-28-29 nM iqinisekisa ukusebenza okusebenzayo kwendlela ye-Wnt.
- Ukusetyenziswa kwemixholo: Ngokuyintloko ifundelwe izicelo zendawo, ezifana nokuvuselelwa kwefollicle yeenwele.
- Ukucoceka okuphezulu: Ucoceko lwe-99% luqinisekisa ukusebenza okuthembekileyo kuphando kunye nezifundo zonyango.
Ulwazi Lokugcina:
- Gcina e-20°Ckwisitya esivalwe ngokuqinileyo, kwindawo epholileyo neyomileyo, kude nomswakama kunye nokukhanya, ukugcina uzinzo.
Le mveliso yenzelwe iinjongo zophando kuphela kwaye ayisetyenziselwa abantu okanye izilwanyana. Ngee-odolo ezininzi okanye inkxaso yobugcisa engaphezulu, nceda uqhagamshelane nathi.
Iindlela ezahlukeneyo zokuhlawula onokuthi ukhethe
Isithembiso sethu Kuwe:
Yonke imveliso esiyithengisayo yi-100% eyiNqobo kunye noMgangatho oPhezulu.
Ukwaneliseka kwakho yi-100% eqinisekisiweyo okanye ubuyiselwe imali yakho.
Ukupakisha
· I-1kg/i-aluminium foil bag, eneeplastiki ezimbini ngaphakathi.
· 25kg/ifayibha igubu, kunye neeplastiki ezimbini ngaphakathi.
Ubungakanani: ID 42cm * H52cm, 0.08m3 / idrum;
Ubunzima obuNina: 25kgs Ubunzima obuGqibeleleyo: 28kgs.
Izinto Eziluncedo Zethu
1. UbuNgcali boShishino: -Ngeminyaka yamava kushishino lwamayeza, iqela lethu lizisa ubuchule obuninzi kuphuhliso lwemveliso, ukwenziwa kunye nokuhanjiswa.
2. IiMveliso ezikwiMgangatho oPhezulu: -Sibambelela kwimigangatho engqongqo yolawulo lomgangatho kunye neZenzo zoMveliso eziLungileyo ukuze siqinisekise ukhuseleko kunye nokusebenza ngempumelelo kweemveliso zethu zamayeza.
3. Uluhlu lweeMveliso ezahlukeneyo: -Ipotfoliyo yethu yemveliso ebanzi ibandakanya i-Active Pharmaceutical Ingredients (APIs), iifom zedosi egqityiweyo, abaphakathi bamayeza, kunye nokulungelelanisa.
izisombululo zamachiza ukuhlangabezana noluhlu olubanzi lweemfuno.
4. Ubunakho bokwenza ngokwezifiso: -Sinikezela ngezisombululo ezilungiselelwe uphuhliso lwemveliso yamayeza kunye nokuvelisa ukuhlangabezana neemfuno ezizodwa zabathengi bethu.
5. Ukufikelelwa kweHlabathi:- -Sinobukho obuqinileyo bamazwe aphesheya, okusivumela ukuba sikhonze abathengi kunye namaqabane kwihlabathi liphela. Iimveliso zethu zihanjiswa kwimimandla eyahlukeneyo, ziqinisekisa ukufikeleleka kunye nokuthembeka.
6. Ukuthotyelwa kwemiGaqo:- -Sigcina ukubambelela ngokungqongqo kwimigangatho yolawulo lwamazwe ngamazwe kunye nezikhokelo, siqinisekisa ukuba iimveliso zethu zihlangabezana nazo zonke iimfuno eziyimfuneko zokulawula.
7. Inkxaso yabaThengi abaphendulayo: -Iqela lethu elizinikeleyo lenkxaso kubathengi liyafumaneka ukukunceda ngokukhawuleza ngemibuzo, iiodolo, kunye nenkxaso yobugcisa.
8. Amaxabiso oKhuphiswano: -Sizama ukubonelela ngamaxabiso akhuphisanayo kwiimveliso zethu zamayeza ezikumgangatho ophezulu, okwenza izisombululo ezingabizi kakhulu kubathengi bethu.
9. Iinkqubo eziZinzileyo: -Sizibophelele kwizenzo ezinoxanduva lokusingqongileyo kwiinkqubo zethu zokuvelisa kunye nokusebenza, okunegalelo kwikamva elizinzileyo.
10. Inguqulelo noPhando:-Sityala imali kuphando kunye nophuhliso ukuze sihlale siphambili kwinkqubela phambili yamayeza kunye nokuhambisa iimveliso ezintsha kubathengi bethu.
11. Intsebenziswano yexesha elide:-Sibuxabisa ubudlelwane bexesha elide kunye nabathengi bethu kunye namaqabane, sikhuthaza ukuthembana kunye nentsebenziswano ukuze siphumelele.
12. Unxibelelwano oluselubala:-Sikholelwa kunxibelelwano oluselubala noluvulelekileyo, siqinisekisa ukuba abathengi bethu banolwazi kwaye bazithembile kwiinkqubano zabo nathi.
I-Q1: Indlela yokuqinisekisa umgangatho wemveliso ngaphambi kokubeka umyalelo?
1. Unokufumana iisampuli zeemveliso.
2. Ungaphinda usithumelele iinkcukacha okanye iimfuno zakho, kwaye siya kulungelelanisa imveliso kuwe.
I-Q2: Ndingaqhagamshelana njani nawe?
Qhagamshelana nathi nge-imeyile okanye kuWhatsapp. I-avareji yexesha lokuphendula yi-0-4 iiyure ngeeyure zokusebenza kwaye ngaphantsi kweeyure ezingama-24 ngexesha leeyure ezingasebenziyo.
Q3: Uyenza njani iodolo?
-Qhagamshelana nathi ngayo nayiphi na kwezi ndlela zingasentla..
-Sishiyele umyalezo ngemveliso oyifunayo.
-Inkcazelo yomyalelo Ubungakanani.
-Nceda usixelele idilesi yakho yokuthumela.
–Umphathi wentengiso ukunika ikowuteshini.
-Ukuhanjiswa kosuku olunye emva kwentlawulo.
