Kuphononongo lwakutsha nje oluqhutywe kumzi-mveliso okhokelayo, abaphandi baye bafumanisa indlela yokusebenza kwaye babona iziphumo ezilungileyo ze-pregabalin ekunyangeni ukubanjwa kancinci.Le mpumelelo inika ithemba elitsha kubantu abaphethwe sesi sifo, ihlahl’ indlela yokuqhubela phambili kunyango lokuxhuzula.
Ukuxhuzula okungaphelelanga, okwakwaziwa ngokuba kukuxhuzula okugxilwe kuko, luhlobo lokuxhuzula olusuka kwindawo ethile yobuchopho.Oku kuxhuzula kunokuchaphazela kakhulu umgangatho wobomi bomntu, kaninzi kukhokelela ekuthinteleni kwimisebenzi yemihla ngemihla kunye nokwanda kweengozi zokulimala ngokomzimba.Njengoko ukusebenza konyango olukhoyo kuhleli kunqongophele, abaphandi bebengadinwa besebenzela ukufumana izisombululo ezitsha nezisebenzayo.
I-Pregabalin, iyeza elisetyenziselwa ikakhulu ukunyanga isifo sokuxhuzula, iintlungu ze-neuropathic, kunye nokuphazamiseka kokuxhalaba, libonise isithembiso esikhulu ekulweni nokuxhuzula okungaphelelanga.Uphononongo olwenziweyo lujolise ekuqondeni indlela yokusebenza kwayo kunye nokuvavanya isiphumo salo sonyango kwiqela lezigulane ezixhatshazwayo.
Inkqubo yesenzo se-pregabalin ibandakanya ukubophelela kumajelo athile e-calcium kwinkqubo ye-nervous central, ukunciphisa ukukhululwa kwee-neurotransmitters ezijongene nokuhambisa iimpawu zentlungu kunye nomsebenzi ongaqhelekanga wombane kwingqondo.Ngokuzinzisa i-neurons esebenzayo, i-pregabalin inceda ukuthintela ukusasazeka kweempembelelo zombane ezingaqhelekanga, ngaloo ndlela kuncitshiswa ukuphindaphinda kunye nobunzima bokubanjwa.
Iziphumo ezifunyenwe kwisifundo sokwenziwa kwezinto zazikhuthaza kakhulu.Kwisithuba seenyanga ezintandathu, izigulane ezifumene i-pregabalin njengenxalenye yerejimeni yonyango zifumana ukuhla okukhulu kwinani lokubanjwa okuyingxenye xa kuthelekiswa neqela lokulawula.Ngaphaya koko, abo baphendule ngokufanelekileyo kwi-pregabalin bachaze umgangatho wobomi obuphuculweyo, kubandakanya nokuncipha kokuxhalaba okunxulumene nokuxhuzula kunye nokuphucula ukusebenza kwengqondo.
UGqr. Samantha Thompson, umphandi okhokelayo obandakanyekayo kwisifundo, wabonisa umdla wakhe malunga nezi ziphumo.Ugxininise imfuno engxamisekileyo yokhetho olungcono lonyango kwizigulane ezinokubanjwa ngokuyinxenye kwaye wavuma ukubaluleka kwendlela yokwenza i-pregabalin ekufezekiseni iziphumo ezilungileyo.UGqr. Thompson ukholelwa ukuba olu phando luya kuba negalelo ekuphuhlisweni kongenelelo olujoliswe ngakumbi nolusebenzayo lonyango, ukuzisa isiqabu kubantu abaninzi abachatshazelwa sisifo sokuxhuzula.
Ngaphandle kweziphumo ezithembisayo, abaphandi bagxininise ukubaluleka kophando olongezelelweyo ukuqinisekisa ezi ziphumo kunye nokuphonononga iziphumo ezinokuthi zibekho kwixesha elide.Kubalulekile ukwenza ulingo lwezonyango olubandakanya abantu abaninzi bezigulane kunye namaqela ahlukeneyo oluntu ukuqinisekisa ukusebenza kunye nokhuseleko lwe-pregabalin ekunyangeni ukuxhuzula okungaphelelanga.
Impumelelo yolu phononongo olwenziweyo luvule iindlela ezintsha zophononongo lwezenzululwazi.Abaphandi babona kwangaphambili uphando lwexesha elizayo olujolise ekwandiseni inkqubo yesenzo se-pregabalin, ukumisela idosi efanelekileyo, kunye nokuchonga indibaniselwano enokubakho namanye amachiza e-antiepileptic ukomeleza ukusebenza kwawo.
Ukuqukumbela, uphononongo olwenziweyo kwindlela yesenzo se-pregabalin kunye neziphumo zayo ezilungileyo ekunyangeni ukuxhuzula okuyinxalenye yinkqubela ebalulekileyo kuphando lokuxhuzula.Le nkqubela phambili ibambe amandla okuguqula imeko yonyango kubantu abaphethwe yile meko inzima.Njengoko uphando olongezelelweyo luqhubeka, kuyathenjwa ukuba i-pregabalin iya kunika isiqabu kwabo bachaphazelekayo kukuhlutha inxalenye, ekugqibeleni baphucule umgangatho wabo wobomi.
Ixesha lokuposa: Jul-07-2023